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ALTADENA - SOUTH PASADENA - SAN MARINO
Mountain View News Saturday, November 25, 2023
San Marino Upcoming
Events & Programming
Paper: Brain Circuit Controls
if Salt Tastes Good or Bad
Representatives Urge NASA to
Reverse Cuts to Mars Program
Representative Adam Schiff and U.S. Senator Alex Padilla
(D-Calif) led a bipartisan and bicameral letter Wednesday,
joined by U.S. Senator Laphonza Butler (D-Calif) and
Representatives Judy Chu, Mike Garcia (R-Calif.), and Young
Kim (R-Calif.), urging NASA Administrator Bill Nelson to
reverse unilateral funding cuts to the Mars Sample Return
(MSR) mission, which would result in the loss of hundreds of
California jobs, ensure the Jet Propulsion Laboratory (JPL)
misses its 2030 launch window, and lead to the cancelation
of billions of dollars in contracts supporting American
businesses.
Full letter text below:
Dear Administrator Nelson,
We write to express our strongest opposition to
NASA’s recent unilateral and unprecedented decision
to prematurely move forward with funding cuts to the
Mars Sample Return (MSR) mission before Congress has
finalized its Fiscal Year 2024 appropriations process. This
short-sighted and misguided decision by NASA will cost
hundreds of jobs and a decade of lost science, and it flies in
the face of Congressional authority.
The 2023 Planetary Sciences Decadal Survey identified
the completion of MSR as NASA’s highest scientific priority.
For the first time in human history, we would launch a
spacecraft from the surface of another planet and give our
scientists the opportunity to directly analyze samples from
Mars. The capabilities demonstrated and science returned
by MSR would ensure American leadership with regard to
Mars and pave the way for eventual human exploration of
the planet. Furthermore, space technological innovation is
a critical aspect of our ongoing strategic competition with
China and Russia.
The recently commissioned Independent Review Board
(IRB) assessment of the MSR Program’s implementation
plan and management approach reiterated that MSR should
be a national space exploration priority, given its scientific
and strategic importance. Coupled with changes in the
NASA program management structure of MSR and the
expeditious finalization of modified mission architecture,
funding levels consistent with FY 2023 levels are necessary
to ensure a launch no later than 2030 to get samples into
the orbit of Mars.
China is rapidly expanding its space program with a new
space station, a goal of landing taikonauts on the moon by
the end of this decade, a stated intention of being the first
to return samples from Mars, and an aggressive vision for
more ambitious endeavors such as building infrastructure
in space, missions to the outer solar system, and creating
a space governance system. U.S. Space Force General B.
Chance Saltzman, chief of space operations, said in March
2023 that the U.S. must maintain a status of “perpetual
competition.” The MSR mission is critical to staying well
ahead of the competition in strategic space technologies,
meeting the national security challenge posed by China,
and maintaining our current competitive advantage.
It is important to note that the House appropriations bill
that funds NASA recognizes the critical nature of the MSR
mission and would fund it at $949.3 million, equal to the
President’s Budget request, and includes the following
direction:
Mars Sample Return.—The Committee supports
consistent funding for the Mars Sample Return mission.
The Committee directs NASA to allocate no less than
$949,300,000 for this mission. In accordance with
the pending Independent Review Board’s results, and
considering the existing architecture committed to
successfully returning samples to Earth, the Committee
directs NASA to ensure that its fiscal year 2025 budget
request includes the funding necessary to complete the
mission launch no later than 2030.
Therefore, we are mystified by NASA’s rash decision to
suggest at this stage of the appropriations process that
any cuts would be necessary. If forced to operate at the
unnecessarily low funding level prematurely directed
by NASA in its November 8 letter, the Jet Propulsion
Laboratory (JPL) will not be able to meet the 2030
launch window, billions of dollars in contracts supporting
American businesses will be subject to cancellation, and
hundreds of highly skilled jobs in California will be lost.
This talent represents a national asset that we cannot afford
to lose, and if this uniquely talented workforce is lost to the
private sector, it will be near impossible to reassemble.
NASA’s deeply short-sighted and misguided decision
to unilaterally adjust the funding allocation granted to
JPL to carry out the MSR mission violates Congress’s
appropriations authority. Therefore, we strongly urge you to
rescind NASA’s November 8th funding directive to JPL and
not take any further steps to adjust funding levels for the
mission until Congress enacts final FY24 appropriations for
NASA.
We look forward to working with you to complete Fiscal
Year 2024 appropriations legislation that fully funds NASA
–including the MSR program, promotes our national
security priorities in space, and keeps the United States
at the forefront of scientific and technical achievement in
space.
For More information visit: schiff.house.go.
New research from Caltech
scientists is showing us more
about how the brain regulates
when the flavor of salt is yuck
or yum.
Having the right amount of
sodium in your body is so
crucial, in fact, that parts of your
brain work hard to make sure
you’re getting the salt that you
need. If you’ve ever been hit by a
sudden craving for potato chips,
that may have been your brain
at work. On the other hand,
if you’re thirsty, salted snacks
might sound like the last thing
you to eat.
“Low sodium concentration
is palatable, while higher
concentrations—for example,
ocean water—taste disgusting,”
says Yuki Oka, Professor of
Biology and Heritage Medical
Research Institute Investigator.
“But when you’re really in need
of salt, you don’t mind the
bad taste. The palatability or
‘tastiness’ of salt changes based
on its concentration and the
body’s internal sodium need.”
The body meticulously
regulates blood sodium levels
to stay within a narrow range
of 135 to 145 millimolar. This is
accomplished through precise
control of salt consumption
and retention. To keep sodium
levels precisely balanced,
the brain must control both
attraction and aversion to salt.
In 2019, researchers in the Oka
lab discovered the brain circuit
that drives cravings for salt in
mice. Stimulating these “salt-
appetite” neurons, located at
the base of the skull in a region
called the hindbrain, triggered
an immediate appetite for salty
food. But the mechanisms
regulating an aversion to salty
tastes remained unanswered.
New findings from the Oka lab
reveal a distinct neural circuit
in the mouse brain responsible
for regulating tolerance towards
the negative taste associated
with sodium. These neurons
are located in the forebrain, far
from the salt-appetite neurons.
Unlike the previously identified
salt-appetite neurons, activation
of the tolerance neurons does
not prompt active seeking of
sodium. Instead, activity of these
neurons enables mice to accept
or tolerate high levels of salt
that would usually be aversive,
in order to efficiently replete
sodium levels in the body.
Blocking the tolerance neurons
results in mice rejecting aversive
salt, even if low on sodium.
The simultaneous operation
of forebrain tolerance and
hindbrain appetite circuits is
crucial for maintaining sodium
levels within the body.
The researchers found that
the tolerance neurons are not
directly connected to the salt
appetite neurons, and appear to
function independently. How,
then, does the body regulate the
activity of the newly discovered
circuits?
The new study shows that,
intriguingly, the tolerance
neurons have receptors for
the hormone prostaglandin
E2 (PGE2) on their surfaces,
suggesting that their activity
is modulated by this hormone
circulating through the
bloodstream. This is a novel
revelation—prostaglandin,
commonly associated with
inflammation, had not
previously been linked to
sodium intake. According to
Yameng Zhang, a graduate
student in the Oka lab and the
lead author of the new study,
“This unexpected association
between prostaglandin and
sodium consumption raises
important questions regarding
how an inflammatory state
might influence sodium intake,
offering new insights into the
interplay between sodium
levels and the body’s pro-
inflammatory condition.”
The results are reported in a
paper appearing in the journal
Cell on November 20.
The paper is titled “Parallel
Neural Pathways Control
Sodium Consumption and
Taste Valence.” A graduate
student, Yameng Zhang is the
first author, with additional co-
authors from Caltech including
graduate student Tongtong
Wang, former postdoctoral
scholar Allan-Hermann Pool
(now an assistant professor
at the University of Texas,
Southwestern), postdoctoral
scholar Lu Liu, and former
Caltech undergraduate Elin
Kang.
Yuki Oka (pictured) is a
member of the Tianqiao and
Chrissy Chen Institute for
Neuroscience at Caltech.
Shop 'till You Drop Holiday Shopping Shuttle to Citadel
Outlets, Commerce
Tuesday, December 5 from 10 AM – 5 PM
Cost: R: $8 / NR: $10
Time to get all your holiday shopping out of the way! Active
adults ages 55 and up are invited to join us for a daytime
shopping trip. Transportation is provided. Reserve your spot
online!
Tween Holiday Prep Shop
Thursday, December 7 at 3:30 PM, Barth Community Room
Is your tween looking for the perfect gift for friends and
family? Then send them on down to our one-stop shop to
choose, create, and wrap holiday crafts to give. All materials
will be provided at this exclusive tween-only (grades 4-6)
event. Registration is recommended.
Home for the Holidays: Light Up San Marino!
Registration: November 26 - December 10
Voting: December 11 - 17
Do you have the most festive home or business in town?
Enter our 3rd annual holiday decorating contest! Online
registration will be open November 26 - December 10.
Entries will be placed on the Holiday Decorating Contest
map on December 11. This year, 3 winning entries will be
selected by the Mayor, Recreation Commission, and YOU!
Community members have the opportunity to participate
by voting for their favorite entries by “liking” them on
Facebook. Winners will receive a gold-ribbon yard sign and
gift card to The Huntington Store.
Home for the Holidays: Tree Lighting Ceremony &
Mayor's Reception
Friday, December 8 from 5 PM - 7 PM, Corner of Huntington
Drive and San Marino Avenue
Join us as we kick-off Home for the Holidays festivities.
There will be a warm holiday glow around City Hall to honor
the 71-year history of the Holiday House Bus Shelter: A San
Marino Tradition. Join us for the tree lighting ceremony and
watch Santa arrive by fire truck. In addition, there will be
photos with Santa and Mrs. Claus, hot dogs, hot chocolate
and cider, holiday cookies, festive selfie stations, kid’s
craft table, and performances by the Valentine and Carver
Elementary School Choir. Event is FREE and everyone is
welcome!
West Nile Virus Detected
The city was notified that a mosquito trapped in San
Marino tested positive for West Nile Virus. Public health
agencies detect West Nile virus every year in L.A. County,
which means it's endemic and found naturally in our city
environments. City staff are working with the Greater Los
Angeles County Vector Control District (GLACVCD) to
monitor the situation. For questions regarding mosquito
inspections and testing, contact GLACVCD at (562) 944-
9656. To read more about West Nile Virus and what you can
do to protect yourself and your family, visit: glamosquito.
org/west-nile-virus.
Meetings
Library Board of Trustees
Monday, November 27 at 8:00 AM; Barth Room and Zoom
(Public Access)
Design Review Committee
Wednesday, December 6 at 6:00 PM; Barth Room and Zoom.
San Marino Board Member
Needed for the GLACVCD
Decem
The City of San Marino
seeks a volunteer to fill an
opening as a Board Member
on the Greater Los Angeles
County Vector Control
(Mosquito Abatement)
District Board of Trustees.
San Marino residency is
required, and the member
appointed shall be an elector
of the City. Board member
duties and responsibilities
include setting policy,
establishing the budget,
approving expenditures,
and retaining legal counsel.
More information about
GLACVCD can be
found at: glamosquito.
org. Applications are due
November 30. If you have
questions regarding this
recruitment, please contact
the City Clerk at (626) 300-
0705 or CityClerk@
CityofSanMarino.org.
Further details and the
application can be found
at: cityofsanmarino.org/
government.
Early Literacy Family Workshop
at the South Pasadena Library
The South Pasadena Public
Library is offering an Early
Literacy Family Workshop,
Playing, Discovering,
Reflecting, on December 6
from 10:00 a.m. -11:00 a.m.
in the Library Community
Room at 1115 El Centro
Street, South Pasadena, CA.
This workshop is designed
for children ages 2- to
4-years old and their parents
and caregivers. During
the workshop, parents and
caregivers will learn about
creating learning experiences
and environments that
support the development
of their child’s complex
intellectual thinking, deep
conceptual thinking, and
creative problem-solving
abilities – skills that will
help them throughout their
lives and better prepare
them for school. After a
brief discussion of research
that outlines the skills and
conditions that matter
most for a child’s success in
school, the children and their
caregivers will rotate through
three creative, fun, open-
ended, hands-on activities.
All supplies will be provided.
Registration is required and
will be limited to the first 40
people.
Sign up for this event
at: southpasadenaca.gov/
register or contact the
Children’s Services Librarians
at childrenlibrarian@
southpasadenaca.gov or
(626)403-7358 for any
questions.
The South Pasadena
Public Library is located at
1100 Oxley Street in South
Pasadena. Visit the Library
website at https://www.
southpasadenaca.gov for
information about services
and programs. The Library
is open Monday, Friday,
Saturday 10:00 AM–6:00
PM, Tuesday, Wednesday,
Thursday 10:00 AM–8:00
PM and Sunday 1:00 PM–
5:00 PM.
Friends of the Pasadena
Library Bookstore to Open
The Friends of the Pasadena
Public Library (FOPPL)
Bookstore will open soon
with a variety of used books,
DVDs, CDs, LPs and lots
and lots of children’s books
for you to select from. They
are targeting Tuesday Jan. 9,
as an opening date. Look for
more details to follow in the
January/February issue of Off
the Shelf at: cityofpasadena.
net/library.
The new bookstore location
is the former Jefferson
Elementary School campus,
1500 E. Villa Ave. (between
Hill and Allen), east of the
Jefferson Library Branch.
Opening hours will be
Tuesday, Thursday and
Saturdays from 11 a.m. to 4
p.m. They hope to expand
the hours in a few months.
A donation bin is located
to the east of the Jefferson
Branch Library on the
grass near the huge tree.
Donations will be accepted
only at this location not at
any branch libraries. We are
accepting all used books
in good condition, except
textbooks, magazines and
cassettes. For large
donations, contact Adrienne
at phrogg8@gmail.com to
make an appointment.
Mountain Views News 80 W Sierra Madre Blvd. No. 327 Sierra Madre, Ca. 91024 Office: 626.355.2737 Fax: 626.609.3285 Email: editor@mtnviewsnews.com Website: www.mtnviewsnews.com
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